How Arthritis Injections for Knees Are Revolutionizing Joint Care

Interview with Dr. Kevin O’Donnell | Revitalize Regenerative Orthopedics

What are the most common types of injections used to treat knee arthritis, and how do they differ in their mechanisms and effectiveness?

The most common injections for knee arthritis include corticosteroids, platelet-rich plasma (PRP), and stem cell therapies. Each has a unique mechanism of action and varying levels of effectiveness. Corticosteroids reduce inflammation and provide short-term pain relief but don't address the underlying cause. PRP, derived from a patient’s own blood, contains growth factors that promote healing and tissue repair. Stem cell therapies aim to regenerate damaged tissues and provide long-term relief. The choice of treatment depends on the severity of arthritis, the patient’s goals, and cost considerations.

Can you discuss the role of regenerative therapies such as stem cell injections in treating knee arthritis and provide an example of a case study?

Regenerative therapies like  Micronized Adipose (MFAT) and Bone Marrow Concentrate have shown significant promise in treating knee arthritis. In my practice, knees respond most predictably well to these treatments. For instance, I assess a patient's arthritis severity, budget, and functional goals before recommending a specific therapy.

One example: A 75-year-old man with severe arthritis and limited mobility might benefit from prolotherapy or PRP to achieve moderate pain relief and improved functionality. On the other hand, a 45-year-old marathon runner with the same condition might require more aggressive stem cell treatment to sustain high activity levels. Regenerative therapies allow us to personalize care based on these individual needs and goals.

When should someone consider Regenerative treatments for knee arthritis?

Many people turn to regenerative treatments after exhausting home remedies like over-the-counter medication, compression sleeves, or heat/ice therapy. If pain persists or worsens over three months despite these efforts, it’s often time to explore additional options.

Regenerative therapies can bridge the gap between basic home care and invasive surgeries, offering relief and improved function without significant downtime. While awareness of these treatments has improved over the last decade, many people still don't realize they’re a viable option.

Do patients need a referral to access Regenerative treatments?

No referral is necessary to see us. Patients can self-refer or come through recommendations from physical therapists, chiropractors, or other physicians. While some insurance carriers may require a referral, most of our patients come to us directly.

What post-injection care or lifestyle modifications do you recommend to enhance treatment effectiveness?

Post-injection care typically includes bracing to offload the treated area, and in some cases, crutches for one to three days. Physical therapy is essential for restoring range of motion, rebuilding surrounding muscles, and progressively loading the tissue to promote healing. We also recommend supplements tailored to the type of injury or condition, such as those for tendon or muscle repair and osteoarthritis support. Combining these strategies—injections, physical therapy, bracing, and supplements—maximizes healing and long-term outcomes.

How can regenerative treatments help maintain mobility and independence as patients age?

Aging often leads to reduced muscle mass, known as sarcopenia, which can limit mobility and increase the risk of falls. Regenerative treatments can address joint pain and dysfunction, enabling patients to stay active and maintain lower body strength. This is crucial for independence and daily activities, such as getting up from a chair or walking up stairs.

For older patients, preserving strength and mobility is not just about reducing joint pain but also about maintaining overall quality of life.

How do you see the future of regenerative treatments advancing over the next five years?

With the aging baby boomer generation and increased awareness of non-surgical options, the demand for regenerative treatments will likely grow. As treatments become more refined and accessible, they will play a critical role in preventing joint replacements and managing arthritis-related pain. Advances in technology and research will likely lead to even more effective therapies that help patients remain active and independent.

Will health insurance ever cover regenerative treatments?

While some military insurances, like Tricare, already cover PRP for specific conditions, widespread adoption by insurers hasn’t happened yet. I’ve been optimistic about this for the past decade, but significant progress remains to be seen. Preventive treatments like these could save costs on larger surgeries, and I’m hopeful insurance coverage will expand in the future.

Do you see many military or former military patients in your practice?

Occasionally, though I would like to see more. Many military personnel face long-term joint issues from the physical demands of their service. These conditions often resurface years later, making regenerative treatments a viable and effective option for managing chronic pain and improving function.

Key Takeaways you should know when considering arthritis injections for your knees:

1. Regenerative treatments, including PRP and stem cell therapies, offer promising solutions for managing knee arthritis and are tailored to individual patient needs.
2. These therapies can bridge the gap between home remedies and invasive surgeries, providing relief and improved function without significant downtime.
3. Post-treatment care, including physical therapy and supplements, is essential for maximizing outcomes and maintaining long-term joint health.

Regenerative treatments for knee arthritis provide an effective, non-invasive option for reducing pain, improving mobility, and maintaining independence. Whether you’re managing persistent joint pain or exploring alternatives to surgery, we’re here to help. Book an assessment today with Revitalize Regenerative Orthopedics, which includes a detailed 90-minute consultation and ultrasound evaluation, to determine the best treatment plan for your needs.